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Hyper-IgM syndrome
Hyper-IgM syndrome is characterized by normal or elevated levels of immunoglobulin M (IgM) and decreased levels or the absence of other immunoglobulins. As a result, people are more susceptible to bacterial infections. Children with hyper-IgM syndrome have frequent infections of the sinuses and lungs.The disorder is diagnosed by measuring the concentration of immunoglobulins in the …
Lepidoptera BAC Clones
Conservation and lineage-specific rearrangements in the GOBP/PBP gene complex of distantly related ditrysian Lepidoptera. General odorant binding proteins (GOBPs) and pheromone binding proteins (PBPs) form a monophyletic subfamily of insect odorant binding proteins (OBPs) specific for Lepidoptera, butterflies and moths. The GOBP/PBP genes include six subgroups (GOBP1-2, PBP-A-D) previously reported to form a complex arrayed …
Symbio
Orally applied bacterial lysate in infants at risk for atopy does not prevent atopic dermatitis, allergic rhinitis, asthma or allergic sensitization at school age: follow-up of a randomized trial. The allergy preventive effects of gut immune modulation by bacterial compounds are still not fully understood.We sought to evaluate the effect of bacterial lysate applied orally …